Identification and Biological Characteristics of an Antifungal Compound Extracted from Cocklebur (Xanthium strumarium) against Phytophthora drechsleri

Kim, Dong Kil; Shim, Chang Ki; Bae, Dong Won; Kawk, Yeon Sik; Yang, Min Suk; Kim, Hee Kyu

doi:2002.18.5.288

Plant Pathol J > Volume 18(5); 2002 > Article

The Plant Pathology Journal 2002;18(5):288-292.
DOI: https://doi.org/10.5423/PPJ.2002.18.5.288 Published online October 31, 2002.

Identification and Biological Characteristics of an Antifungal Compound Extracted from Cocklebur (Xanthium strumarium) against Phytophthora drechsleri

Dong Kil Kim, Chang Ki Shim, Dong Won Bae, Yeon Sik Kawk, Min Suk Yang, Hee Kyu Kim

Abstract

Crude extracts of Xanthium strumarium inhibited mycelial growth and zoospore germination of Phytophthora drechsleri, the causal agent of Atractylis rot, in vitro. Fresh sap from X. strumarium at 50-fold dilution was highly effective in controlling the disease incidence in pot and field trials. Purified extracts from cocklebur inhibited mycelial growth and zoospore germination in vitro at a concentration of 12.5 mg/ml and 15.6 mg/ml, respectively. Hyphal tips affected by the compound showed malformation. The antifungal compound purified from X. strumarium was identified as 4-oxo-1 (5), 2,11, (13)-xanthatriene-12,8-olide, known as "deacetyl xanthumin".

Key Words: antifungal compound, Atractylis, deacetyl xanthumin, Phytophthora dechsleri, Xanthium strumarium