Plant Pathol J > Volume 23(4); 2007 > Article
The Plant Pathology Journal 2007;23(4):318-321.
DOI:    Published online December 31, 2007.
Nematicidal Activity of Bikaverin and Fusaric Acid Isolated from Fusarium oxysporum against Pine Wood Nematode, Bursaphelenchus xylophilus
Hyeok Ran Kwon, Seung Wan Son, Hye Rim Han, Gyung Ja Choi, Kyoung Soo Jang, Yong Ho Choi, Sun Og Lee, Nack Do Sung, Jin Cheol Kim
Pine wood nematode, Bursaphelenchus xylophilus, causes pine wilt disease in a number of Pinus species, which is one of the most serious plant diseases in forest, Korea. In the course of a search for nematicidal substances from endophytic fungi, Fusarium oxysporum EF119 out of the 23 fungal strains tested showed the strongest activity to B. xylophilus. Two nematicidal substances were isolated and identified as bikaverin and fusaric acid. Fusaric acid showed somewhat higher nematicidal activity against B. xylophilus than bikaverin; fusaric acid and bikaverin, at 100 μg/ml, killed B. xylophilus with mortality values of 50% and 43%, respectively. In addition, both compounds acted synergistically. This is the first report on the nematicidal activity of bikaverin and fusaric acid.
Key Words: Bursaphelenchus xylophilus, bikaverin, fusaric acid, Fusarium oxysporum, nematicidal activity, pine wood nematode

Editorial Office
Rm,904 (New Bldg.) The Korean Science & Technology Center 22,
Teheran-ro 7-Gil, Gangnamgu, Seoul 06130, Korea
Tel: +82-2-557-9360    Fax: +82-2-557-9361    E-mail:                

Copyright © 2024 by Korean Society of Plant Pathology.

Developed in M2PI

Close layer
prev next